A "Complete Interior" treatment, is highly recommended first.
OZONE eliminates the irritation caused by phenol gases, by oxidizing them. Phenol gases are the invisible part of tobacco smoke that causes such discomfort to one’s eyes and creates offensive odors. Ozone rids any environment of the effects of smoke completely, rather than merely filtering out some of the visible particles like an electronic air cleaner or air filter system.
For car interiors, "atomized tar"(cigarette smoke) gets EVERYWHERE and must be removed EVERYWHERE before the smell is TRULY gone (as seen in this video). The last step is OZONE treatment. Ozone gas reaches into the vent system, breaks down and neutralizes the tar molecules. This is crucial for car vents since most people cannot reach into the AC vent system without completely tearing apart the dashboard and vent tubes.